The Eisack Valley wine-growing region extends from the municipality of Varna/Vahrn (near Bressanone/Brixen) in the north, to Bolzano/Bozen in the south. The glacial valley around Bressanone is closed like an amphitheater on its northern end, which helps to protect it from colder air currents. The vineyards are mostly located here, especially on the left-facing side, where the vines warm up quickly due to the strong sunlight and steep slopes. The sandy, gravelly moraine soil is made up of a mixture of shale, gneiss and granite.

Beyond this cirque above Bressanone, the Eisacktal Valley narrows and turns slightly to the southwest; the vineyards here are built mainly on the right side. From the area south of Bressanone to below Chiusa/Klausen, the stone is mainly quartz phyllite; below Ponte Gardena/Waidbruck it is mainly quartz porphyry. Glacial remains and interglacial alluvial deposits are distributed across the entire valley. As a result, the soil is permeable, and can thus absorb heat quickly.

The soil's high silicate content gives the wines from Eisacktal Valley their characteristic mineral note.